Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889038 | 0.99 | MAPK8 (0.48) | MAPK8KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL8888556 | 0.94 | MAPK8 (0.49) | MAPK8KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL11447309 | 0.84 | MAPK8 (0.62) | MAPK8KDM4EALDH1A1HPGDMAPK9 | |
| SCHEMBL11701910 | 0.80 | ADORA1 (0.52) | MAPK8KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL9468248 | 0.78 | MAPK8 (0.46) | MAPK8KDM4EALDH1A1HPGDGAA | |
| SCHEMBL13514208 | 0.74 | MAPK8 (0.43) | MAPK8MAPK9MAPK10 | |
| SCHEMBL11702984 | 0.74 | MAPK8 (0.43) | MAPK8KDM4EALDH1A1HPGDGAA | |
| SCHEMBL11608749 | 0.72 | KDM4E (0.40) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL8963971 | 0.72 | MAPK8 (0.44) | MAPK8KDM4EALDH1A1HPGDGAA | |
| SCHEMBL28748293 | 0.72 | ADORA1 (0.56) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602238-A | FOR DYEING POLYESTER FIBERS COLORFAST RED SHADES | CIBA-GEIGY CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0699718-A2 | Azothiophene dyes with a 2,4,6-triamino-3-cyanopyridine coupling component | CIBA-GEIGY AG (CH) | 1996-03-06 | — | — | EP | disclosed |