Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30275033 | 0.86 | L3MBTL1 (0.47) | L3MBTL1HSD17B10LMNAIDH1TP53 | |
| SCHEMBL11814419 | 0.85 | KCNA5 (0.61) | HSD17B10LMNAPPP1CAKCNA5SMN1; SMN2 | |
| SCHEMBL11813355 | 0.83 | IDH1 (0.49) | L3MBTL1LMNAIDH1PPP1CAKCNA5 | |
| SCHEMBL11880541 | 0.78 | L3MBTL1 (0.42) | L3MBTL1HSD17B10LMNAIDH1TP53 | |
| SCHEMBL11639513 | 0.77 | CHRM2 (0.42) | L3MBTL1HSD17B10LMNAIDH1TP53 | |
| SCHEMBL11821540 | 0.76 | MAPT (0.42) | L3MBTL1HSD17B10LMNAIDH1TP53 | |
| Hydrochloric Acid SCHEMBL11635049 | 0.76 | LMNA (0.43) | L3MBTL1HSD17B10LMNAIDH1TP53 | |
| SCHEMBL16464338 | 0.74 | L3MBTL1 (0.49) | L3MBTL1HSD17B10LMNAIDH1TP53 | |
| SCHEMBL11878537 | 0.74 | KCNA5 (0.44) | L3MBTL1HSD17B10LMNAIDH1TP53 | |
| SCHEMBL16461215 | 0.74 | DPP4 (0.56) | L3MBTL1HSD17B10LMNAIDH1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118567-A | 3-Morpholino-2-heterocyclic-thiopropanamides | SMITHKLINE CORPORATION (US) | 1978-10-03 | — | — | US | disclosed |
| US-3933811-A | N-aminomethyl-2-amino(and 2-amino-methyl)-2-(2-quinolyl)-thioacetamides | SMITHKLINE CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |