Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11643883 | 0.96 | OPRM1 (0.45) | OPRM1OPRK1OPRL1ALDH1A1GSK3B | |
| SCHEMBL3524191 | 0.76 | ALDH1A1 (0.48) | OPRM1OPRK1OPRL1ALDH1A1GSK3B | |
| SCHEMBL11640312 | 0.73 | HRH3 (0.34) | OPRM1OPRK1OPRL1ALDH1A1HSD17B10 | |
| SCHEMBL19216470 | 0.72 | GSK3B (0.59) | ALDH1A1GSK3BPDK2PDK4APOBEC3A | |
| SCHEMBL30548926 | 0.72 | GSK3B (0.59) | ALDH1A1GSK3BPDK2PDK4APOBEC3A | |
| SCHEMBL2573765 | 0.72 | GSK3B (0.59) | ALDH1A1GSK3BPDK2PDK4APOBEC3A | |
| SCHEMBL3523663 | 0.71 | MEN1 (0.44) | OPRM1OPRK1OPRL1ALDH1A1GSK3B | |
| SCHEMBL4892684 | 0.71 | ALDH1A1 (0.41) | OPRM1OPRK1OPRL1ALDH1A1GSK3B | |
| SCHEMBL11642045 | 0.69 | ALDH1A1 (0.35) | OPRM1OPRK1OPRL1ALDH1A1POLB | |
| SCHEMBL10836894 | 0.69 | OPRM1 (0.39) | OPRM1OPRK1OPRL1ALDH1A1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123543-A | ANTIDEPRESSANTS | AB KABI (SE) | 1978-10-31 | — | — | US | claimed |