Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3675034 | 0.78 | HPGD (0.46) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| SCHEMBL12204783 | 0.78 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL4806049 | 0.76 | CES2 (0.60) | HPGDERCC5FEN1ALDH1A1POLB | |
| SCHEMBL30725459 | 0.76 | CES2 (0.60) | HPGDERCC5FEN1ALDH1A1POLB | |
| SCHEMBL28677921 | 0.76 | KDM4E (0.54) | HPGDHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27930379 | 0.75 | TP53 (0.41) | HPGDHTTALDH1A1KMT2A | |
| SCHEMBL16891474 | 0.75 | NPC1 (0.36) | HPGDALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL19332963 | 0.74 | CES2 (0.58) | HPGDERCC5FEN1HTTCTNNB1 | |
| SCHEMBL18104841 | 0.74 | NPC1 (0.43) | HPGDSMN1; SMN2ALDH1A1HSD17B10POLB | |
| SCHEMBL17244263 | 0.74 | MAPT (0.50) | HPGDSMN1; SMN2ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263933-A | Alpha-carboline derivative and synthesis method thereof | 湘潭大学 | 2023-12-22 | — | — | CN | claimed |
| CN-117263933-A | Alpha-carboline derivative and synthesis method thereof | 湘潭大学 | 2023-12-22 | — | — | CN | disclosed |
| US-4117135-A | NOVEL 5,6,7,8-TETRAHYDRO-5-QUINOLINES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCHERING, A.G. | 1978-09-26 | — | — | US | disclosed |