Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855430 | 0.79 | CYP3A4 (0.43) | MAPTCYP3A4MAPK1TDP1LMNA | |
| SCHEMBL11643098 | 0.78 | MAPT (0.37) | MAPTCYP3A4MAPK1TDP1LMNA | |
| SCHEMBL8855435 | 0.77 | TDP1 (0.44) | MAPTCYP3A4MAPK1TDP1LMNA | |
| SCHEMBL8855520 | 0.76 | MAPT (0.39) | MAPTCYP3A4MAPK1LMNACYP1A2 | |
| SCHEMBL11645452 | 0.76 | CYP2C9 (0.43) | MAPTCYP3A4TDP1LMNAGAA | |
| SCHEMBL11859665 | 0.76 | CYP3A4 (0.43) | MAPTCYP3A4MAPK1TDP1LMNA | |
| SCHEMBL11648114 | 0.76 | MEN1 (0.38) | MAPTCYP3A4TDP1LMNAGAA | |
| SCHEMBL8855463 | 0.73 | ESR1 (0.39) | MAPTCYP3A4MAPK1TDP1LMNA | |
| SCHEMBL8855415 | 0.73 | CYP3A4 (0.42) | MAPTCYP3A4MAPK1TDP1LMNA | |
| SCHEMBL11644928 | 0.73 | CYP3A4 (0.37) | MAPTCYP3A4MAPK1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122184-A | Benzimidazole insecticides | ELI LILLY AND COMPANY (US) | 1978-10-24 | — | — | US | disclosed |