Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATF1 | P18846 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | HPD | P32754 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855582 | 0.86 | ESR1 (0.39) | ESR1CYP3A4MAPK1MAPTLMNA | |
| SCHEMBL11641483 | 0.85 | CYP3A4 (0.38) | ESR1CYP3A4MAPK1MAPTLMNA | |
| SCHEMBL8855430 | 0.77 | CYP3A4 (0.43) | CYP3A4MAPK1MAPTLMNAGAA | |
| SCHEMBL8855495 | 0.77 | ESR1 (0.42) | ESR1CYP3A4MAPK1MAPTLMNA | |
| SCHEMBL11644925 | 0.75 | CYP3A4 (0.37) | CYP3A4MAPK1MAPTLMNAGAA | |
| SCHEMBL11644928 | 0.75 | CYP3A4 (0.37) | CYP3A4MAPK1MAPTLMNAGAA | |
| SCHEMBL8855595 | 0.75 | CYP3A4 (0.37) | CYP3A4MAPK1MAPTLMNAGAA | |
| SCHEMBL8855435 | 0.75 | TDP1 (0.44) | CYP3A4MAPK1MAPTLMNAGAA | |
| SCHEMBL11859665 | 0.74 | CYP3A4 (0.43) | CYP3A4MAPK1MAPTLMNAGAA | |
| SCHEMBL11643162 | 0.73 | THRA (0.38) | CYP3A4MAPK1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670485-A | FEEDS FOR POULTRY WITH O-PHENYLENEDIAMINE OR BENZIMIDAZOLE WITH POLYETHER ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1997-09-23 | — | — | US | disclosed |