Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11646493 | 0.85 | PTPN7 (0.59) | PTPN7RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL1312768 | 0.85 | PTPN7 (0.72) | PTPN7RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL2790888 | 0.82 | GRM4 (0.64) | RAB9AMEN1KMT2ANPC1GRM4 | |
| SCHEMBL9925462 | 0.81 | KDM4E (0.68) | PTPN7RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL12916784 | 0.81 | NPC1 (0.63) | RAB9AMEN1KMT2ANPC1GRM4 | |
| SCHEMBL11646389 | 0.77 | PTPN7 (0.59) | PTPN7RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11650077 | 0.77 | PTPN7 (0.59) | PTPN7RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9787019 | 0.77 | PTPN7 (0.59) | PTPN7RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11647637 | 0.77 | LMNA (0.63) | PTPN7RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL7053124 | 0.77 | PTPN7 (0.59) | PTPN7RAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111962-A | Certain substituted 2-phenylnaphtho[1,2-b]furane and -[2,1-b]furane | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |