Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22445087 | 0.82 | PTPN7 (0.59) | PTPN7MEN1KMT2APPARGNCOA2 | |
| SCHEMBL11646493 | 0.79 | PTPN7 (0.59) | PTPN7MEN1KMT2APPARGNCOA2 | |
| SCHEMBL7056130 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2ANPSR1RAB9AHPGD | |
| SCHEMBL1312768 | 0.78 | PTPN7 (0.72) | PTPN7MEN1KMT2APPARGNCOA2 | |
| SCHEMBL27194588 | 0.77 | PTPN7 (0.76) | PTPN7MEN1KMT2APPARGNCOA2 | |
| SCHEMBL22671956 | 0.77 | RAB9A (0.66) | PTPN7MEN1KMT2APPARGNCOA2 | |
| SCHEMBL11643263 | 0.77 | PTPN7 (0.56) | PTPN7MEN1KMT2APPARGNCOA2 | |
| SCHEMBL29367022 | 0.75 | PTPN7 (1.00) | PTPN7MEN1KMT2APPARGNCOA2 | |
| SCHEMBL25640 | 0.75 | PTPN7 (1.00) | PTPN7MEN1KMT2APPARGNCOA2 | |
| SCHEMBL6563888 | 0.75 | PTPN7 (0.73) | PTPN7MEN1KMT2APPARGNCOA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941231-B1 | Heteroarylic-arylic diphosphines as chiral ligands | CHEMI SPA (IT) | 2003-05-02 | — | — | EP | disclosed |
| US-6153758-A | Heteroarylic-arylic diphosphines as chiral ligands | CHEMI S.P.A. (IT) | 2000-11-28 | — | — | US | disclosed |