Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165983 | 0.71 | ALDH1A1 (1.00) | ALDH1A1TSHRHIF1ATDP1MEN1 | |
| SCHEMBL9720387 | 0.68 | ALDH1A1 (0.92) | ALDH1A1TSHRHIF1ATDP1MEN1 | |
| Hydrochloric Acid SCHEMBL10715580 | 0.68 | ALDH1A1 (0.92) | ALDH1A1TSHRHIF1ATDP1MEN1 | |
| SCHEMBL11646141 | 0.66 | TSHR (0.39) | ALDH1A1TSHRHIF1ATDP1THRB | |
| Cyclooctane SCHEMBL3271413 | 0.63 | ALDH1A1 (0.79) | ALDH1A1TSHRHIF1ATDP1MEN1 | |
| SCHEMBL11712660 | 0.61 | MEN1 (0.44) | ALDH1A1TSHRHIF1ATDP1MEN1 | |
| SCHEMBL7139855 | 0.60 | ALDH1A1 (0.38) | ALDH1A1TSHRHIF1ATDP1 | |
| SCHEMBL11381598 | 0.59 | ALDH1A1 (0.59) | ALDH1A1TSHRHIF1ATDP1MEN1 | |
| SCHEMBL11380953 | 0.59 | ALDH1A1 (0.60) | ALDH1A1TSHRHIF1ATDP1MEN1 | |
| SCHEMBL11715262 | 0.57 | MEN1 (0.40) | ALDH1A1TSHRHIF1ATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098761-A | DIELS-ALDER ADDUCTS, FOR NITROGEN-FREE POLYMERS | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1978-07-04 | — | — | US | disclosed |
| US-3976722-A | FIRE RETARDANT | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3941758-A | Halogen containing fire retardant additive with improved heat stability | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |