SCHEMBL9720387

SCHEMBL9720387

ClC1=C(Cl)C(Cl)=C(Cl)C(Cl)(Cl)C(Cl)=C1Cl

nearest known ligand 0.92

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.92
TSHR P16473 1/20 0.92
HIF1A Q16665 1/20 0.92
TDP1 Q9NUW8 1/20 0.92
MEN1 O00255 1/20 0.53
THRB P10828 1/20 0.53
RECQL P46063 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL165983 0.96 ALDH1A1 (1.00) ALDH1A1TSHRHIF1ATDP1MEN1
Hydrochloric Acid SCHEMBL10715580 0.92 ALDH1A1 (0.92) ALDH1A1TSHRHIF1ATDP1MEN1
Cyclooctane SCHEMBL3271413 0.85 ALDH1A1 (0.79) ALDH1A1TSHRHIF1ATDP1MEN1
SCHEMBL2637337 0.77 ALDH1A1 (0.56) ALDH1A1TSHRHIF1ATDP1MEN1
Naphthalene SCHEMBL5080748 0.75 TSHR (0.61) ALDH1A1TSHRHIF1ATDP1MEN1
SCHEMBL5025868 0.74 ALDH1A1 (0.62) ALDH1A1TSHRHIF1ATDP1MEN1
SCHEMBL11381598 0.72 ALDH1A1 (0.59) ALDH1A1TSHRHIF1ATDP1MEN1
SCHEMBL11380953 0.72 ALDH1A1 (0.60) ALDH1A1TSHRHIF1ATDP1MEN1
Dienochlor SCHEMBL117767 0.70 MEN1 (1.00) ALDH1A1TSHRHIF1ATDP1MEN1
SCHEMBL7625810 0.70 MEN1 (0.57) ALDH1A1TSHRHIF1ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5114896-A Reaction product of magnesium, halogenated hydrocarbon, alkoxy compound, titanium compound, halogen-containing alcohol and solid halogenated hydrocarbon TONEN CORPORATION (JP) 1992-05-19 US disclosed
EP-0440813-A1 METHOD OF PRODUCING CATALYST COMPONENT FOR OLEFIN POLYMERIZATION Tonen Corporation (JP) 1991-08-14 EP disclosed