Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SGK1 | O00141 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17280181 | 0.79 | MEN1 (0.43) | SMN1; SMN2PDGFRBGSK3BXDHADORA2A | |
| SCHEMBL17279786 | 0.79 | MEN1 (0.46) | SMN1; SMN2PDGFRBGSK3BADORA3ADORA2A | |
| SCHEMBL17280174 | 0.79 | METAP2 (0.41) | SMN1; SMN2PDGFRBALDH1A1MAPTGAA | |
| SCHEMBL17280243 | 0.78 | CYP1A1 (0.49) | SMN1; SMN2PDGFRBGSK3BADORA2AADORA1 | |
| SCHEMBL7139559 | 0.77 | HPGDS (0.43) | SMN1; SMN2GSK3BXDHALDH1A1MAPT | |
| SCHEMBL4847155 | 0.77 | HPGDS (0.43) | SMN1; SMN2GSK3BXDHALDH1A1MAPT | |
| SCHEMBL528246 | 0.77 | MEN1 (0.46) | SMN1; SMN2PDGFRBGSK3BADORA2AADORA1 | |
| SCHEMBL5128314 | 0.76 | CYP1A1 (0.56) | SMN1; SMN2PDGFRBADORA2AADORA1ALDH1A1 | |
| SCHEMBL31305440 | 0.76 | CYP1A1 (0.56) | SMN1; SMN2PDGFRBADORA2AADORA1ALDH1A1 | |
| SCHEMBL31660297 | 0.76 | CA12 (0.47) | SMN1; SMN2ALDH1A1ADORA2BKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000208-A1 | Process for the preparation of imidazoles | BASF Aktiengesellschaft (DE) | 1979-01-10 | — | — | EP | disclosed |