Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.58 |
| ▸ | AR | P10275 | 7/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647082 | 0.86 | AR (0.61) | PGRARNR3C2LMNANR3C1 | |
| SCHEMBL11645068 | 0.84 | PGR (0.56) | PGRARNR3C2LMNANR3C1 | |
| SCHEMBL7864494 | 0.83 | PGR (0.55) | PGRARNR3C2LMNANR3C1 | |
| SCHEMBL2833264 | 0.81 | PGR (0.62) | PGRARNR3C2LMNANR3C1 | |
| Gestadienol SCHEMBL931512 | 0.79 | AR (0.65) | PGRARNR3C2LMNANR3C1 | |
| SCHEMBL10890105 | 0.78 | PGR (0.73) | PGRARNR3C2LMNANR3C1 | |
| SCHEMBL11645201 | 0.78 | CYP3A4 (0.66) | PGRARNR3C2LMNANR3C1 | |
| SCHEMBL11647042 | 0.78 | PGR (0.73) | PGRARNR3C2LMNANR3C1 | |
| SCHEMBL11809654 | 0.77 | PGR (0.64) | PGRARNR3C2LMNANR3C1 | |
| SCHEMBL11644766 | 0.76 | PGR (0.50) | PGRARNR3C2LMNANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118488-A | 4-Androsten-3-ones and process for the preparation thereof | SCHERING AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |