Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 3/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197830 | 0.86 | EGFR (0.59) | EGFRMAPK14HPGDCNR1CNR2 | |
| SCHEMBL11645912 | 0.84 | EGFR (0.60) | EGFRMAPK14HPGDSMN1; SMN2TDP1 | |
| SCHEMBL11648697 | 0.82 | EGFR (0.57) | EGFRMAPK14HPGDSMN1; SMN2TDP1 | |
| SCHEMBL28628201 | 0.82 | EGFR (0.57) | EGFRMAPK14HPGDSMN1; SMN2TDP1 | |
| SCHEMBL11642518 | 0.82 | EGFR (0.57) | EGFRMAPK14HPGDSMN1; SMN2TDP1 | |
| SCHEMBL11647584 | 0.81 | EGFR (0.56) | EGFRMAPK14HPGDSMN1; SMN2TDP1 | |
| SCHEMBL164064 | 0.81 | EGFR (0.62) | EGFRMAPK14HPGDSMN1; SMN2TDP1 | |
| SCHEMBL4894612 | 0.81 | EGFR (0.62) | EGFRMAPK14HPGDSMN1; SMN2TDP1 | |
| SCHEMBL16245661 | 0.80 | EGFR (0.55) | EGFRMAPK14HPGDSMN1; SMN2TDP1 | |
| SCHEMBL11641649 | 0.80 | EGFR (0.55) | EGFRMAPK14HPGDSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4116671-A | HERBICIDES | SHIONOGI & CO., LTD. (JP) | 1978-09-26 | — | — | US | claimed |