Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | RAF1 | P04049 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164064 | 1.00 | EGFR (0.62) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL16943756 | 0.87 | EGFR (0.59) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL11645912 | 0.84 | EGFR (0.60) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL2951112 | 0.84 | RAB9A (0.77) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL11647584 | 0.84 | EGFR (0.56) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL1758718 | 0.82 | EGFR (0.66) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4112548 | 0.82 | EGFR (0.66) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10804234 | 0.82 | RAF1 (0.62) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL11648697 | 0.82 | EGFR (0.57) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL11642518 | 0.82 | EGFR (0.57) | EGFRNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3906245-B1 | MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS | DOW SILICONES CORP (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-3645640-B1 | SILICONE-POLYETHER COPOLYMER, METHOD OF PREPARING SAME, AND SEALANT COMPRISING SAME | DOW SILICONES CORP (US) | 2024-03-06 | — | — | EP | disclosed |
| WO-2023215360-A1 | SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORPORATION (US) | 2023-11-09 | — | — | WO | disclosed |
| US-11807775-B2 | Silicone-organic copolymer, sealants comprising same, and related methods | DOW SILICONES CORPORATION (US) | 2023-11-07 | — | — | US | disclosed |
| US-11760841-B2 | Silicone-polycarbonate copolymer, sealants comprising same, and related methods | DOW SILICONES CORPORATION (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3898779-B1 | SILICONE-POLYESTER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORP (US) | 2023-02-08 | — | — | EP | disclosed |
| EP-3898781-B1 | SILICONE-POLYCARBONATE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORP (US) | 2023-01-04 | — | — | EP | disclosed |
| US-20220064383-A1 | SILICONE-POLYACRYLATE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORPORATION | 2022-03-03 | — | — | US | disclosed |
| US-20220064482-A1 | SILICONE-ORGANIC COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORPORATION | 2022-03-03 | — | — | US | disclosed |
| EP-3906245-A1 | MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS | Dow Silicones Corporation (US) | 2021-11-10 | — | — | EP | disclosed |
| US-20140187783-A1 | Hafnium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-07-03 | — | — | US | disclosed |
| US-20140183398-A1 | Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2014-07-03 | — | — | US | disclosed |
| US-20140171547-A1 | Bismuth Containing Complex and Condensation Reaction Curable Compositions and Methods for the Preparation and Use of the Compositions | DOW CORNING CORPORATION | 2014-06-19 | — | — | US | disclosed |
| US-20140135517-A1 | Hydrosilylation Reaction Curable Compositions And Methods For Their Preparation And Use | DOW CORNING CORPORATION (US) | 2014-05-15 | — | — | US | disclosed |
| US-20140100347-A1 | Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2014-04-10 | — | — | US | disclosed |
| US-20140039089-A1 | Compositions Containing Phosphonate Catalysts And Methods For The Preparation And Use Of The Compositions | DOW CORNING CORPORATION (US) | 2014-02-06 | — | — | US | disclosed |
| US-20140018467-A1 | COMPOSITIONS CONTAINING SULFONIC ACID CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2014-01-16 | — | — | US | disclosed |
| US-20080118734-A1 | Coating Compositions | DOW CORNING IRELAND LTD. (IE) | 2008-05-22 | — | — | US | disclosed |
| EP-1744836-A2 | PROCESS AND APPARATUS FOR PLASMA COATING, SUBSTRATES COATED BY THIS METHOD OR APPARATUS | Dow Corning Ireland Limited (IE) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005110626-A2 | PROCESS AND APPARATUS FOR PLASMA COATING, SUBSTRATES COATED BY THIS METOD OR APPARATUS | DOW CORNING IRELAND LIMITED (IE) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135517-A1 | Hydrosilylation Reaction Curable Compositions And Methods For Their Preparation And Use | HIRA, HIRIP3, CROCC | EGFR 933/4885NPC1 4523/4885RAB9A 2718/4885 |
| US-20140183398-A1 | Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, ALG8, CAD | EGFR 1136/4885NPC1 1830/4885RAB9A 1023/4885 |
| US-20140187783-A1 | Hafnium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, HACL2, CROCC | EGFR 1668/4885NPC1 3498/4885RAB9A 2341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.