Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.49 |
| ▸ | RAF1 | P04049 | 3/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11645912 | 0.85 | EGFR (0.60) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL11642518 | 0.83 | EGFR (0.57) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL11648697 | 0.83 | EGFR (0.57) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL3197830 | 0.82 | EGFR (0.59) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL11647584 | 0.82 | EGFR (0.56) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL11645249 | 0.82 | EGFR (0.56) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL164064 | 0.82 | EGFR (0.62) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4894612 | 0.82 | EGFR (0.62) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL11648744 | 0.81 | EGFR (0.55) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL16245661 | 0.81 | EGFR (0.55) | EGFRNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997838-B | Silicone-polyether copolymers, sealants including silicone-polyether copolymers, and related methods | 美国陶氏有机硅公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-110997839-B | Silicone-polyether copolymer, method of preparing silicone-polyether copolymer, and sealant including silicone-polyether copolymer | 美国陶氏有机硅公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-110997840-B | Silicone-polyether copolymers, isocyanate-functionalized silicone-polyether copolymers formed therewith, silicone-polyether-urethane copolymers, sealants including the same, and related methods | 美国陶氏有机硅公司 | 2021-09-07 | — | — | CN | disclosed |