Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.40 |
| ▸ | KDR | P35968 | 6/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | RET | P07949 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.40 |
| ▸ | STK3 | Q13188 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.40 |
| ▸ | LATS1 | O95835 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647567 | 0.88 | HSD17B10 (0.49) | HSD17B10NPSR1MAPK1SMN1; SMN2FGFR1 | |
| SCHEMBL11647596 | 0.86 | HSD17B10 (0.42) | HSD17B10NPSR1MAPK1SMN1; SMN2FGFR1 | |
| SCHEMBL11644035 | 0.81 | HSD17B10 (0.39) | HSD17B10NPSR1APEX1ALDH1A1GPR17 | |
| SCHEMBL11647467 | 0.81 | PDK2 (0.38) | HSD17B10NPSR1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL547346 | 0.80 | HSD17B10 (0.51) | HSD17B10NPSR1MAPK1SMN1; SMN2FGFR1 | |
| SCHEMBL11650100 | 0.77 | HSD17B10 (0.44) | HSD17B10NPSR1MAPK1SMN1; SMN2FGFR1 | |
| SCHEMBL11648099 | 0.75 | HSD17B10 (0.40) | HSD17B10NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25046458 | 0.75 | NPSR1 (0.49) | HSD17B10NPSR1MAPK1SMN1; SMN2FGFR1 | |
| SCHEMBL6366738 | 0.75 | HSD17B10 (0.44) | HSD17B10NPSR1FGFR1KDRPDGFRB | |
| SCHEMBL11649627 | 0.75 | HSD17B10 (0.42) | HSD17B10NPSR1APEX1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070366-A | RING ALKYLATION OF SUBSTITUTED PYRROLES, ONE STEP | CANADIAN PATENTS & DEVELOPMENT LIMITED (US) | 1978-01-24 | — | — | US | disclosed |