Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | FLT1 | P17948 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647596 | 0.88 | HSD17B10 (0.42) | HSD17B10P2RX7APEX1GPR17EGFR | |
| SCHEMBL11649627 | 0.87 | HSD17B10 (0.42) | HSD17B10P2RX7APEX1GPR17EGFR | |
| SCHEMBL11647567 | 0.86 | HSD17B10 (0.49) | HSD17B10P2RX7APEX1GPR17EGFR | |
| SCHEMBL547346 | 0.81 | HSD17B10 (0.51) | HSD17B10APEX1GPR17EGFRNPSR1 | |
| SCHEMBL11644035 | 0.79 | HSD17B10 (0.39) | HSD17B10P2RX7APEX1GPR17EGFR | |
| SCHEMBL11645293 | 0.77 | HSD17B10 (0.45) | HSD17B10APEX1GPR17EGFRNPSR1 | |
| SCHEMBL11653208 | 0.77 | HSD17B10 (0.39) | HSD17B10RAB9ATSHRKDM4EALDH1A1 | |
| SCHEMBL6366738 | 0.76 | HSD17B10 (0.44) | HSD17B10APEX1GPR17EGFRNPSR1 | |
| SCHEMBL11647005 | 0.74 | HSD17B10 (0.43) | HSD17B10POLBRAB9AATMPDGFRB | |
| SCHEMBL14560302 | 0.74 | FGFR1 (0.42) | HSD17B10P2RX7APEX1GPR17EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070366-A | RING ALKYLATION OF SUBSTITUTED PYRROLES, ONE STEP | CANADIAN PATENTS & DEVELOPMENT LIMITED (US) | 1978-01-24 | — | — | US | disclosed |