SCHEMBL547346

SCHEMBL547346

Cc1[nH]c(C)c(CCC(=O)O)c1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.51
APEX1 P27695 1/20 0.44
FGFR1 P11362 6/20 0.44
KDR P35968 6/20 0.44
PDGFRB P09619 5/20 0.44
AURKA O14965 2/20 0.44
RET P07949 2/20 0.44
FLT1 P17948 2/20 0.44
FLT3 P36888 2/20 0.44
MAP4K2 Q12851 2/20 0.44
STK3 Q13188 2/20 0.44
AURKB Q96GD4 2/20 0.44
GAK O14976 1/20 0.44
RPS6KA5 O75582 1/20 0.44
RPS6KA4 O75676 1/20 0.44
LATS1 O95835 1/20 0.44
CSNK2A2 P19784 1/20 0.44
MAP2K2 P36507 1/20 0.44
ZAP70 P43403 1/20 0.44
MAP2K1 Q02750 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25046458 0.82 NPSR1 (0.49) HSD17B10APEX1FGFR1KDRPDGFRB
SCHEMBL11650100 0.81 HSD17B10 (0.44) HSD17B10APEX1FGFR1KDRPDGFRB
SCHEMBL11647567 0.81 HSD17B10 (0.49) HSD17B10APEX1FGFR1KDRPDGFRB
SCHEMBL11647596 0.80 HSD17B10 (0.42) HSD17B10APEX1FGFR1KDRPDGFRB
SCHEMBL16090230 0.80 HSD17B10 (0.45) HSD17B10APEX1FGFR1KDRPDGFRB
SCHEMBL14560302 0.80 FGFR1 (0.42) HSD17B10APEX1FGFR1KDRPDGFRB
SCHEMBL11645293 0.80 HSD17B10 (0.45) HSD17B10APEX1FGFR1KDRPDGFRB
SCHEMBL1981272 0.80 KDR (0.51) HSD17B10APEX1FGFR1KDRPDGFRB
SCHEMBL28830916 0.77 NPSR1 (0.50) HSD17B10NPSR1GPR17EGFRKDM4E
SCHEMBL5612750 0.76 NPSR1 (0.74) NPSR1MAPK1SMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9120768-B2 Compositions and methods for treatment of cystic fibrosis and diseases associated with aberrant protein cellular processing THE HOSPITAL FOR SICK CHILDREN (CA) 2015-09-01 US disclosed
US-8967781-B2 Image recording composition, image recording ink set and recording apparatus FUJI XEROX CO., LTD. (JP) 2015-03-03 US disclosed
US-8342672-B2 Recording apparatus FUJI XEROX CO., LTD. (JP) 2013-01-01 US disclosed
US-8246158-B2 Image recording composition, image recording ink set and recording apparatus FUJI XEROX CO., LTD. (JP) 2012-08-21 US disclosed
US-8197921-B2 Ink-recipient particle, material for recording, recording apparatus and storage member for ink-recipient particle FUJI XEROX CO., LTD. (JP) 2012-06-12 US disclosed
WO-2012021974-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF CYSTIC FIBROSIS AND DISEASES ASSOCIATED WITH ABERRANT PROTEIN CELLULAR PROCESSING THE HOSPITAL FOR SICK CHILDREN (CA) 2012-02-23 WO disclosed
US-8110611-B2 Composition for image recording, image recording ink set, and recording apparatus FUJI XEROX CO., LTD. (JP) 2012-02-07 US disclosed
US-8109626-B2 Recording device and ink receiving particles FUJI XEROX CO., LTD. (JP) 2012-02-07 US disclosed
US-8029123-B2 Material set for recording and recording apparatus FUJI XEROX CO., LTD. (JP) 2011-10-04 US disclosed
CN-101391517-B Recording apparatus and recording material FUJITSU XEROX CORP 2011-09-28 CN disclosed
US-20060061640-A1 Ink-jet ink sets, ink-jet ink tanks, ink-jet recording methods, and ink-jet recording apparatuses FUJI XEROX CO., LTD. 2006-03-23 US disclosed
US-20060023042-A1 Liquid composition for ink jet, ink set for ink jet, ink jet recording method and ink jet recording apparatus FUJI XEROX CO., LTD. 2006-02-02 US disclosed
CN-1715052-A Ink jet recording method and ink jet recording apparatus FUJI XEROX CO LTD (JP) 2006-01-04 CN disclosed
US-20050264630-A1 Ink jet recording method and ink jet recording apparatus FUJI XEROX CO., LTD. 2005-12-01 US disclosed
US-20050259138-A1 Ink jet recording method and ink jet recording apparatus FUJI XEROX CO., LTD. 2005-11-24 US disclosed
US-20050244592-A1 Recording paper and image recording method FUJI XEROX CO., LTD. (JP) 2005-11-03 US disclosed
US-20050166792-A1 Ink set for ink-jet recording, ink-jet recording method and ink-jet recording apparatus FUJI XEROX CO., LTD. (JP) 2005-08-04 US disclosed
US-20050003223-A1 Recording sheet and image recording method using the same FUJI XEROX CO., LTD. (JP) 2005-01-06 US disclosed
US-20040244645-A1 Ink set for ink jet recording, ink jet recording method and ink jet recording apparatus FUJI XEROX CO., LTD. (JP) 2004-12-09 US disclosed
US-4070366-A RING ALKYLATION OF SUBSTITUTED PYRROLES, ONE STEP CANADIAN PATENTS & DEVELOPMENT LIMITED (US) 1978-01-24 US disclosed