Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 6/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642716 | 0.93 | MTNR1B (0.64) | MTNR1BTSHRALDH1A1L3MBTL1MTNR1A | |
| SCHEMBL1980614 | 0.90 | MTNR1B (0.80) | MTNR1BTSHRALDH1A1MTNR1ATP53 | |
| SCHEMBL11637763 | 0.90 | MTNR1B (0.80) | MTNR1BTSHRALDH1A1MTNR1ATP53 | |
| SCHEMBL11645434 | 0.89 | XIAP (0.58) | MTNR1BTSHRALDH1A1NPC1RAB9A | |
| SCHEMBL11645837 | 0.86 | CDK8 (0.53) | MTNR1BTSHRALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL11645404 | 0.85 | MTNR1B (0.63) | MTNR1BTSHRALDH1A1MTNR1ANPC1 | |
| SCHEMBL11646067 | 0.85 | XIAP (0.54) | MTNR1BTSHRALDH1A1TP53NPC1 | |
| SCHEMBL11644195 | 0.85 | XIAP (0.48) | MTNR1BTSHRALDH1A1RAB9AKMT2A | |
| SCHEMBL11645013 | 0.85 | XIAP (0.54) | MTNR1BTSHRALDH1A1L3MBTL1NPC1 | |
| SCHEMBL11641056 | 0.84 | MTNR1B (0.60) | MTNR1BTSHRALDH1A1MTNR1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |