Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 8/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642968 | 0.94 | MTNR1B (0.56) | MTNR1BMTNR1AALDH1A1TSHRHPGD | |
| SCHEMBL11642407 | 0.90 | MITF (0.57) | ALDH1A1TSHRHPGDMAPTRAB9A | |
| SCHEMBL11643510 | 0.87 | LTA4H (0.54) | MTNR1BALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11666949 | 0.86 | S1PR2 (0.53) | MTNR1BALDH1A1MEN1KMT2A | |
| SCHEMBL11764331 | 0.86 | KMT2A (0.52) | MTNR1BALDH1A1MEN1NPC1MAPT | |
| SCHEMBL11644122 | 0.86 | CDK8 (0.49) | MTNR1BALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11646842 | 0.86 | MEN1 (0.52) | MTNR1BALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11644410 | 0.86 | S1PR2 (0.53) | MTNR1BALDH1A1SMN1; SMN2 | |
| SCHEMBL11642722 | 0.85 | HPGD (0.56) | MTNR1BMTNR1AHPGDNPC1RAB9A | |
| SCHEMBL11644068 | 0.85 | MTNR1B (0.47) | MTNR1BMTNR1AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |