Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 6/20 | 0.56 |
| ▸ | KLK7 | P49862 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11639881 | 0.90 | LTA4H (0.59) | LMNAS1PR1S1PR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL11647275 | 0.90 | S1PR1 (0.58) | LMNATP53S1PR1S1PR3SMN1; SMN2 | |
| SCHEMBL11643760 | 0.90 | S1PR1 (0.57) | LMNATP53S1PR1S1PR3ALDH1A1 | |
| SCHEMBL11645467 | 0.89 | MAPT (0.60) | S1PR1S1PR3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11641623 | 0.89 | TSHR (0.52) | LMNAS1PR1S1PR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL11644742 | 0.88 | S1PR1 (0.59) | LMNAS1PR1S1PR3ALDH1A1MEN1 | |
| SCHEMBL11647845 | 0.87 | S1PR1 (0.58) | LMNAS1PR1S1PR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL11644156 | 0.87 | SMN1; SMN2 (0.56) | S1PR1S1PR3ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11691654 | 0.87 | ALDH1A1 (0.61) | S1PR1S1PR3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11643286 | 0.87 | LTA4H (0.56) | S1PR1S1PR3ALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-4021571-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |
| US-4005123-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-25 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |