Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL6 | Q9H5J4 | 4/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11641150 | 0.89 | GABRR1 (0.41) | ELOVL6MMP8ALDH1A1MMP3CYP2C19 | |
| SCHEMBL11642582 | 0.89 | GABRR1 (0.44) | ELOVL6MMP8ALDH1A1MMP3CYP2C19 | |
| SCHEMBL2048495 | 0.75 | HTR2A (0.59) | MMP8ALDH1A1AKR1C3HTR2AMAPT | |
| SCHEMBL9727592 | 0.75 | HTR2A (0.49) | ELOVL6MMP8ALDH1A1AKR1C3HTR2A | |
| SCHEMBL27095423 | 0.75 | HTR2A (0.45) | ELOVL6MMP8ALDH1A1AKR1C3HTR2A | |
| SCHEMBL11792229 | 0.71 | AKR1C3 (0.49) | AKR1C3HTR2AAKR1C1GABRR1 | |
| SCHEMBL16863988 | 0.71 | HTR2A (0.56) | ELOVL6ALDH1A1AKR1C3HTR2AMAPT | |
| SCHEMBL11120903 | 0.71 | HTR2A (0.51) | ELOVL6ALDH1A1AKR1C3HTR2AMAPT | |
| Cyanide SCHEMBL27638463 | 0.70 | HTR2A (0.54) | MMP8ALDH1A1AKR1C3HTR2AMAPT | |
| SCHEMBL24483682 | 0.70 | HTR2A (0.41) | ELOVL6MMP8ALDH1A1AKR1C3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |