Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | ELOVL6 | Q9H5J4 | 4/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11120903 | 0.89 | HTR2A (0.51) | HTR2AMAPTKCNH2HTR2CELOVL6 | |
| SCHEMBL2048495 | 0.82 | HTR2A (0.59) | HTR2AMAPTMMP13MMP8MMP1 | |
| SCHEMBL24483682 | 0.80 | HTR2A (0.41) | HTR2AMAPTMMP13MMP8MMP1 | |
| SCHEMBL9727592 | 0.78 | HTR2A (0.49) | HTR2AMAPTMMP13MMP8MMP1 | |
| SCHEMBL7212033 | 0.77 | MMP13 (0.71) | HTR2AMAPTMMP13MMP8MMP1 | |
| SCHEMBL16863988 | 0.77 | HTR2A (0.56) | HTR2AMAPTKCNH2HTR2CELOVL6 | |
| SCHEMBL11090180 | 0.77 | TSHR (0.64) | MAPTMMP13MMP8MMP1SMN1; SMN2 | |
| Cyanide SCHEMBL27638463 | 0.76 | HTR2A (0.54) | HTR2AMAPTMMP13MMP8MMP1 | |
| SCHEMBL11645759 | 0.75 | ELOVL6 (0.40) | HTR2AMAPTMMP13MMP8MMP1 | |
| SCHEMBL777971 | 0.74 | MAPT (0.56) | HTR2AMAPTMMP13MMP8MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240058456-A1 | MOLECULES WITH SOLUBILITY TAG AND RELATED METHODS | MERCK KGAA (DE) | 2024-02-22 | — | — | US | disclosed |
| EP-4213884-A1 | MOLECULES WITH SOLUBILITY TAG AND RELATED METHODS | Merck Patent GmbH (DE) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022058548-A1 | MOLECULES WITH SOLUBILITY TAG AND RELATED METHODS | MERCK PATENT GMBH (DE) | 2022-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240058456-A1 | MOLECULES WITH SOLUBILITY TAG AND RELATED METHODS | STT3B, STT3A, CD2BP2 | HTR2A 3477/4885MAPT 943/4885MMP13 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.