Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.57 |
| ▸ | MC3R | P41968 | 1/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.57 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.57 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.57 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11702678 | 0.84 | ADORA2B (0.64) | SMN1; SMN2ADORA2BPIK3CDPOLBADORA3 | |
| SCHEMBL5471122 | 0.83 | ADORA2B (0.62) | SMN1; SMN2ADORA2BPIK3CDPOLBADORA3 | |
| SCHEMBL7020240 | 0.83 | ADORA2B (0.62) | SMN1; SMN2ADORA2BPIK3CDPOLBADORA3 | |
| SCHEMBL11635125 | 0.80 | ADORA2B (0.58) | SMN1; SMN2ADORA2BPIK3CDPOLBADORA3 | |
| SCHEMBL11702913 | 0.80 | ADORA2B (0.58) | SMN1; SMN2ADORA2BPIK3CDPOLBADORA3 | |
| SCHEMBL11702624 | 0.79 | ADORA2B (0.57) | SMN1; SMN2ADORA2BPIK3CDPOLBADORA3 | |
| SCHEMBL11632640 | 0.79 | ADORA2B (0.57) | SMN1; SMN2ADORA2BPIK3CDPOLBADORA3 | |
| SCHEMBL684080 | 0.79 | ADORA2B (0.57) | SMN1; SMN2ADORA2BPIK3CDPOLBADORA3 | |
| SCHEMBL11641580 | 0.79 | PDE4A (0.44) | SMN1; SMN2ADORA2BADORA2ALMNAMEN1 | |
| SCHEMBL11430962 | 0.78 | ADORA2B (0.56) | SMN1; SMN2ADORA2BPIK3CDPOLBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4120947-A | Xanthine compounds and method of treating bronchospastic and allergic diseases | COOPER LABORATORIES, INC. (US) | 1978-10-17 | — | — | US | disclosed |