Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.62 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.62 |
| ▸ | MC3R | P41968 | 1/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.62 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.62 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.62 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11702678 | 0.88 | ADORA2B (0.64) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| SCHEMBL7020240 | 0.87 | ADORA2B (0.62) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| SCHEMBL11635125 | 0.84 | ADORA2B (0.58) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| SCHEMBL11702913 | 0.84 | ADORA2B (0.58) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| SCHEMBL684080 | 0.83 | ADORA2B (0.57) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| SCHEMBL11632640 | 0.83 | ADORA2B (0.57) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| SCHEMBL11645874 | 0.83 | SMN1; SMN2 (0.60) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| SCHEMBL11702624 | 0.83 | ADORA2B (0.57) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| SCHEMBL11430962 | 0.81 | ADORA2B (0.56) | ADORA2BPOLBPIK3CDADORA3CNR1 | |
| SCHEMBL11705193 | 0.81 | RXFP1 (0.61) | ADORA2BPOLBPIK3CDADORA3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1358178-A | Pharmaceutical compounds | NICOX SA (FR) | 2002-07-10 | — | — | CN | claimed |
| CN-119923380-A | N-substituted phenylalkylamines and their use as therapeutic agents | 亚历山大舒尔金研究所有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-119185329-A | Application of galanthamine, niclosamide, ethyloltheophylline and thiocolchicoside compound in preparation of product for inhibiting SpCas9 from binding or cutting substrate | 中国人民解放军空军军医大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-119053326-A | Capsaicin derivatives as bioenhancers of active substances metabolized by CYP1A2 and CYP2D6 | 艾克西化学公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-113423435-A | Treatment of respiratory disorders using arachidonic acid 15-lipoxygenase (ALOX15) inhibitors | 雷杰纳荣制药公司 | 2021-09-21 | — | — | CN | disclosed |
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | NAFTCHI N E | 2007-04-12 | — | — | US | disclosed |
| US-7109329-B2 | Neurologically active compounds and compounds with multiple activities | NAFTCHI N ERIC | 2006-09-19 | — | — | US | disclosed |
| CN-1358178-A | Pharmaceutical compounds | NICOX SA (FR) | 2002-07-10 | — | — | CN | disclosed |
| US-6413962-B1 | ANESTHESIA AND TEMPERATURES REDUCTION; ALPHA-ADRENOCEPTOR AGONIST; RESTORATIVE TO CENTRAL NERVOUS SYSTEM, ESPECIALLY MOTOR AND SENSORY FUNCTIONAL LOSSES FROM TRAMATIC SPINAL CORD INJURIES; ANTISPASTICS; NONSEDATIVE; SIDE EFFECT REDUCTION | NAFTCHI N ERIC (US) | 2002-07-02 | — | — | US | disclosed |
| US-4883801-A | Xanthine derivative pest control agents | THE GENERAL HOSPITAL CORPORATION (US) | 1989-11-28 | — | — | US | disclosed |
| EP-0193599-A1 | XANTHINE DERIVATIVE PEST CONTROL AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 1986-09-10 | — | — | EP | disclosed |
| WO-1986001724-A1 | XANTHINE DERIVATIVE PEST CONTROL AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 1986-03-27 | — | — | WO | disclosed |
| US-4085214-A | ANTIASTHMA | INTERX RESEARCH CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-4002756-A | Useful pro-drug forms of theophylline | INTERX RESEARCH CORPORATION (US) | 1977-01-11 | — | — | US | disclosed |
| US-4000132-A | REACTION WITH CARBOXYLIC ACID, PHOSGENE, OR THIONYL CHLORIDE | INTERX RESEARCH CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3935196-A | Useful pro-drug forms of theophylline | INTERX RESEARCH CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | ADRB2, ADRB1, CHRNA7 | ADORA2B 115/4885POLB 2849/4885PIK3CD 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.