Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | C1R | P00736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642499 | 0.75 | MAOB (0.56) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL2246201 | 0.74 | RAB9A (0.63) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL11646375 | 0.73 | MAOB (0.55) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11644349 | 0.73 | MAOB (0.55) | MAPTRAB9ANPC1SMN1; SMN2MAOB | |
| SCHEMBL11643516 | 0.73 | MAOB (0.51) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL2246143 | 0.73 | RAB9A (1.00) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL14693776 | 0.72 | MMP2 (0.56) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL14693753 | 0.71 | MEN1 (0.60) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL11645101 | 0.70 | MAOB (0.51) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11647116 | 0.70 | MAOB (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4131677-A | Anti-inflammatory oxazolo [5,4-b]pyridines | MERCK & CO., INC. (US) | 1978-12-26 | — | — | US | disclosed |
| US-4038396-A | ANTIPYRETICS, ANALGESICS | MERCK & CO., INC. (US) | 1977-07-26 | — | — | US | disclosed |