Germacrene D

Germacrene D

SCHEMBL1164630

C=C1/C=C\C(C(C)C)CC/C(C)=C\CC1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MET P08581 5/20 0.47
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CNR2 P34972 1/20 0.39
PPARA Q07869 1/20 0.39
TAS2R46 P59540 3/20 0.38
PKM P14618 2/20 0.38
RECQL P46063 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TERT O14746 1/20 0.38
PTPN1 P18031 1/20 0.34
ALDH1A1 P00352 4/20 0.33
LMNA P02545 4/20 0.33
TP53 P04637 3/20 0.33
CYP3A4 P08684 3/20 0.33
NLRP3 Q96P20 2/20 0.33
NFKB1 P19838 2/20 0.33
CYP1A2 P05177 2/20 0.33
STAT6 P42226 2/20 0.33
MAPT P10636 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Germacrene D SCHEMBL30105561 1.00 MET (0.47) METMEN1KMT2ACNR2PPARA
Germacrene D SCHEMBL113144 1.00 MET (0.47) METMEN1KMT2ACNR2PPARA
Germacrene D SCHEMBL2522883 1.00 MET (0.47) METMEN1KMT2ACNR2PPARA
Germacrene D SCHEMBL113142 1.00 MET (0.47) METMEN1KMT2ACNR2PPARA
Germacrene D SCHEMBL29974910 1.00 MET (0.47) METMEN1KMT2ACNR2PPARA
SCHEMBL30105602 0.98 MET (0.49) METMEN1KMT2ACNR2PPARA
Beta-Phellandrene SCHEMBL154149 0.82 MET (0.31) MET
Beta-Phellandrene SCHEMBL17629433 0.82 MET (0.31) MET
Beta-Phellandrene SCHEMBL1306441 0.82 MET (0.31) MET
Beta-Phellandrene SCHEMBL2531709 0.82 MET (0.31) MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119060791-A Plant compound essential oil capable of relieving anxiety 北京林业大学 2024-12-03 CN claimed
US-12319899-B1 Beverage additive DALE ROBERT (US) 2025-06-03 US disclosed
US-20250009857-A1 NUTRACEUTICAL COMPOSITION BASED ON PINEAPPLE AND PLANT EXTRACTS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME AUTONOMOUS UNIVERSITY OF NUEVO LEON (UANL) (UNIVERSIDAD AUTONOMA DE NUEVO LEON) (MX) 2025-01-09 US disclosed
CN-119060791-A Plant compound essential oil capable of relieving anxiety 北京林业大学 2024-12-03 CN disclosed
CN-119060791-A Plant compound essential oil capable of relieving anxiety 北京林业大学 2024-12-03 CN disclosed
US-20240189737-A1 COMPOSITIONS FOR LOW-TEMPERATURE DISTILLATION OF HIGH-BOILING-POINT MOLECULES Natural Extraction Systems, LLC 2024-06-13 US disclosed
US-20240181369-A1 PRODUCTS AND METHODS RELATED TO THE DISTILLATION OF MOLECULES FROM AEROSOLS Natural Extraction Systems, LLC 2024-06-06 US disclosed
WO-2024073146-A2 COMPOSITIONS FOR LOW-TEMPERATURE DISTILLATION OF HIGH-BOILING-POINT MOLECULES Natural Extraction Systems, LLC (US) 2024-04-04 WO disclosed
WO-2024073142-A1 PRODUCTS AND METHODS RELATED TO THE DISTILLATION OF MOLECULES FROM AEROSOLS Natural Extraction Systems, LLC (US) 2024-04-04 WO disclosed
WO-2024073147-A1 COMPOSITIONS FOR LOW-TEMPERATURE DISTILLATION OF HIGH-BOILING-POINT MOLECULES Natural Extraction Systems, LLC (US) 2024-04-04 WO disclosed
US-8481062-B2 Mixture and method for controlling the insect Acrobasis nuxvorella on Carya illinoiensis plants CENTRO DE INVESTIGACION EN ALIMENTACION Y DESARROLLO A.C. (MX) 2013-07-09 US disclosed
EP-2467120-A2 COMPOSITION FOR CLEANING AND/OR CARING FOR THE SKIN, COMPRISING AN ETHANOLIC AND AQUEOUS HYDRODISPERSIBLE MINT COMPOSITION Kneipp-Werke Kneipp-Mittel-Zentrale GmbH & Co. KG (DE) 2012-06-27 EP disclosed
US-20110251292-A1 MIXTURE AND METHOD FOR CONTROLLING THE INSECT ACROBASIS NUXVORELLA ON CARYA ILLINOIENSIS PLANTS CENTRO DE INVESTIGACION EN ALIMENTACION Y DESARROLLO A.C. (MX) 2011-10-13 US disclosed
WO-2011020759-A2 COMPOSITION FOR CLEANING AND/OR CARING FOR THE SKIN, COMPRISING AN ETHANOLIC AND AQUEOUS HYDRODISPERSIBLE MINT COMPOSITION KNEIPP-WERKE KNEIPP-MITTEL-ZENTRALE GMBH & CO. KG (DE) 2011-02-24 WO disclosed
EP-2286785-A1 Compound for cleaning and/or care of skin with an ethanolic-aqueous hydro-dispersible mint composition Kneipp-Werke Kneipp-Mittel-Zentrale GmbH & Co. KG (DE) 2011-02-23 EP disclosed
US-7312323-B2 Enzymes and polynucleotides encoding the same THE HORTICULTURE AND FOOD RESEARCH INSTITUTE OF NEW ZEALAND LIMITED (NZ) 2007-12-25 US disclosed
US-20060162008-A1 genetic construct, vector coding germacrene-D synthase; producing germacrene as insect attractants/deterrents, antimicrobial agents, fungicides, flavour and fragrance additives; plant terpene synthases; biofermentation processes THE HORTICULTURE AND FOOD RESEARCH INSTITUTE OF NEW ZEALAND LIMITED (NZ) 2006-07-20 US disclosed
EP-1581553-A4 ENZYMES AND POLYNUCLEOTIDES ENCODING THE SAME HORTICULTURE & FOOD RES INST (NZ) 2006-04-26 EP disclosed
EP-1581553-A1 ENZYMES AND POLYNUCLEOTIDES ENCODING THE SAME The Horticulture and Food Research Institute of New Zealand Limited (NZ) 2005-10-05 EP disclosed
WO-2004058814-A1 ENZYMES AND POLYNUCLEOTIDES ENCODING THE SAME THE HORTICULTURE AND FOOD RESEARCH INSTITUTE OF NEW ZEALAND LIMITED (NZ) 2004-07-15 WO disclosed