Germacrene D

Germacrene D

SCHEMBL2522883

C=C1C=CC(C(C)C)CCC(C)=CCC1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MET P08581 5/20 0.47
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CNR2 P34972 1/20 0.39
PPARA Q07869 1/20 0.39
TAS2R46 P59540 3/20 0.38
PKM P14618 2/20 0.38
RECQL P46063 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TERT O14746 1/20 0.38
PTPN1 P18031 1/20 0.34
ALDH1A1 P00352 4/20 0.33
LMNA P02545 4/20 0.33
TP53 P04637 3/20 0.33
CYP3A4 P08684 3/20 0.33
NLRP3 Q96P20 2/20 0.33
NFKB1 P19838 2/20 0.33
CYP1A2 P05177 2/20 0.33
STAT6 P42226 2/20 0.33
MAPT P10636 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Germacrene D SCHEMBL1164630 1.00 MET (0.47) METMEN1KMT2ACNR2PPARA
Germacrene D SCHEMBL30105561 1.00 MET (0.47) METMEN1KMT2ACNR2PPARA
Germacrene D SCHEMBL113144 1.00 MET (0.47) METMEN1KMT2ACNR2PPARA
Germacrene D SCHEMBL113142 1.00 MET (0.47) METMEN1KMT2ACNR2PPARA
Germacrene D SCHEMBL29974910 1.00 MET (0.47) METMEN1KMT2ACNR2PPARA
SCHEMBL30105602 0.98 MET (0.49) METMEN1KMT2ACNR2PPARA
Beta-Phellandrene SCHEMBL154149 0.82 MET (0.31) MET
Beta-Phellandrene SCHEMBL17629433 0.82 MET (0.31) MET
Beta-Phellandrene SCHEMBL1306441 0.82 MET (0.31) MET
Beta-Phellandrene SCHEMBL2531709 0.82 MET (0.31) MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190155975-A9 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions THE PROCTER & GAMBLE COMPANY 2019-05-23 US claimed
US-10240108-B2 Particles for malodor reduction THE PROCTER & GAMBLE COMPANY (US) 2019-03-26 US claimed
US-20180004875-A1 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions THE PROCTER & GAMBLE COMPANY 2018-01-04 US claimed
US-20170333591-A9 ABSORBENT ARTICLE COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2017-11-23 US claimed
US-20170275564-A1 PARTICLES FOR MALODOR REDUCTION PROCTER & GAMBLE (US) 2017-09-28 US claimed
US-20170249408-A1 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions THE PROCTER & GAMBLE COMPANY 2017-08-31 US claimed
US-20170249407-A1 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions THE PROCTER & GAMBLE COMPANY 2017-08-31 US claimed
EP-3197424-A1 FRESHENING COMPOSITIONS AND DEVICES COMPRISING SAME THE PROCTER & GAMBLE COMPANY (US) 2017-08-02 EP claimed
EP-3197511-A1 PERSONAL CARE COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2017-08-02 EP claimed
EP-3197425-A1 SUBSTRATES COMPRISING MALODOR REDUCTION COMPOSITIONS The Procter and Gamble Company (US) 2017-08-02 EP claimed
WO-2016049398-A1 FRESHENING COMPOSITIONS AND DEVICES COMPRISING SAME THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
US-20160090556-A1 PRODUCTS COMPRISING MALODOR REDUCTION MATERIALS THE PROCTER & GAMBLE COMPANY 2016-03-31 US claimed
US-20160090557-A1 SUBSTRATES COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2016-03-31 US claimed
WO-2016049455-A1 PERSONAL CARE COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
WO-2016049407-A1 ABSORBENT ARTICLE COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
US-20160089317-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2016-03-31 US claimed
WO-2016049396-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
WO-2016049404-A1 SUBSTRATES COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
US-20160090555-A1 CLEANING AND/OR TREATMENT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2016-03-31 US claimed
US-20160089318-A1 PERSONAL CARE COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2016-03-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170249408-A1 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions LPO, QDPR, TYR MET 3756/4885MEN1 3913/4885KMT2A 1352/4885
US-20170249407-A1 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions LPO, QDPR, TYR MET 3768/4885MEN1 3949/4885KMT2A 1426/4885
US-20160089317-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS LPO, QDPR, TYR MET 3756/4885MEN1 3913/4885KMT2A 1352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.