Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 12/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 11/20 | 0.68 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.68 |
| ▸ | PRKDC | P78527 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | PDE5A | O76074 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.68 |
| ▸ | TACR2 | P21452 | 1/20 | 0.68 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14231869 | 0.88 | CYP1A1 (0.51) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| SCHEMBL24368484 | 0.87 | CYP1A1 (0.55) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| SCHEMBL24368465 | 0.87 | CYP1A1 (0.55) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| SCHEMBL24368335 | 0.87 | CYP1A1 (0.55) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| SCHEMBL24368466 | 0.87 | CYP1A1 (0.55) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| SCHEMBL24368336 | 0.87 | CYP1A1 (0.55) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| SCHEMBL12279182 | 0.86 | MAOA (0.58) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| SCHEMBL11643109 | 0.86 | MAOB (0.54) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| SCHEMBL11643021 | 0.86 | MAOB (0.62) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| SCHEMBL11645931 | 0.86 | CYP1A1 (0.71) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111962-A | Certain substituted 2-phenylnaphtho[1,2-b]furane and -[2,1-b]furane | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4111962-A | Certain substituted 2-phenylnaphtho[1,2-b]furane and -[2,1-b]furane | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4111962-A | Certain substituted 2-phenylnaphtho[1,2-b]furane and -[2,1-b]furane | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-3781279-A | STILBENE OPTICAL BRIGHTENERS | MOBAY CORPORATION | 1973-12-25 | — | — | US | disclosed |