Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647487 | 1.00 | TSHR (0.43) | TSHRPOLBGLAGAARAB9A | |
| SCHEMBL9611207 | 0.87 | POLB (0.48) | TSHRPOLBGLAGAARAB9A | |
| SCHEMBL11648036 | 0.87 | POLB (0.48) | TSHRPOLBGLAGAARAB9A | |
| SCHEMBL11648927 | 0.85 | POLB (0.38) | TSHRPOLBGLAGAARAB9A | |
| SCHEMBL11648931 | 0.85 | POLB (0.38) | TSHRPOLBGLAGAARAB9A | |
| SCHEMBL20258497 | 0.83 | TSHR (0.59) | TSHRPOLBGLAGAARAB9A | |
| SCHEMBL10035793 | 0.83 | TSHR (0.59) | TSHRPOLBGLAGAARAB9A | |
| SCHEMBL11683549 | 0.82 | CYP3A4 (0.51) | TSHRPOLBRAB9AMEN1KMT2A | |
| SCHEMBL11414728 | 0.78 | RAB9A (0.43) | TSHRPOLBGLAGAARAB9A | |
| SCHEMBL11414723 | 0.78 | RAB9A (0.43) | TSHRPOLBGLAGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093613-A | Trisazo pigments containing two barbituric acid coupling components | CIBA-GEIGY CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4043999-A | Methyl or methoxy substituted iminoisoindolinone pigments | CIBA-GEIGY CORPORATION (US) | 1977-08-23 | — | — | US | disclosed |