Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12455912 | 0.82 | TP53 (0.44) | ALDH1A1TP53MAPK1HPGDL3MBTL1 | |
| SCHEMBL286127 | 0.81 | TP53 (0.46) | ALDH1A1TP53MAPK1HPGDL3MBTL1 | |
| SCHEMBL21401433 | 0.81 | TP53 (0.43) | ALDH1A1TP53MAPK1HPGDL3MBTL1 | |
| SCHEMBL7259530 | 0.81 | TP53 (0.43) | ALDH1A1TP53MAPK1HPGDL3MBTL1 | |
| SCHEMBL11650054 | 0.79 | USP2 (0.46) | ALDH1A1HPGDSMN1; SMN2NPC1HTT | |
| SCHEMBL23562689 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL26469152 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HPGDSMN1; SMN2NPC1HTT | |
| Hydrochloric Acid SCHEMBL23540009 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL24097794 | 0.76 | SMN1; SMN2 (0.34) | ALDH1A1HPGDL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL20086449 | 0.76 | CCNE1 (0.59) | ALDH1A1HPGDL3MBTL1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4089865-A | Certain thiazole compounds | SYNTEX (U.S.A.) INC. (US) | 1978-05-16 | — | — | US | disclosed |
| US-4001421-A | THIAZOLE CARDIOVASCULAR AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-04 | — | — | US | disclosed |