Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12448122 | 0.84 | HCAR2 (0.51) | ALDH1A1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL12449167 | 0.84 | GAA (0.42) | ALDH1A1RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL11648634 | 0.81 | GAA (0.47) | GAAKDM4ENPSR1NAMPT | |
| SCHEMBL11648917 | 0.78 | ALDH1A1 (0.44) | ALDH1A1RAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL11658564 | 0.77 | NAMPT (0.42) | RAB9AGAAKMT2AKDM4ENPSR1 | |
| SCHEMBL11652256 | 0.76 | RECQL (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL11656613 | 0.76 | GAA (0.41) | GAAKDM4ENPSR1NAMPT | |
| SCHEMBL23562689 | 0.75 | ALDH1A1 (0.48) | ALDH1A1RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL11650054 | 0.75 | USP2 (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL11649748 | 0.75 | NAMPT (0.40) | ALDH1A1RAB9AGAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11641857-B2 | Unusually potent ABA receptor pan-antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11641857-B2 | Unusually potent ABA receptor pan-antagonists | AAK1, ATP5PO, BROX | ALDH1A1 4006/4885RAB9A 2150/4885NPC1 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.