Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 3/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.56 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11653150 | 0.79 | PARP10 (0.49) | PARP15PARP10TNKS2PARP2MAPT | |
| SCHEMBL11652422 | 0.75 | PARP2 (0.54) | PARP15PARP10TNKS2PARP2SMN1; SMN2 | |
| SCHEMBL11652246 | 0.73 | PARP15 (0.43) | PARP15PARP10TNKS2PARP2SMN1; SMN2 | |
| SCHEMBL11658117 | 0.72 | PARP15 (0.42) | PARP15PARP10TNKS2PARP2SMN1; SMN2 | |
| SCHEMBL25324784 | 0.72 | TNKS2 (1.00) | PARP15PARP10TNKS2PARP2SMN1; SMN2 | |
| SCHEMBL11652428 | 0.72 | PARP15 (0.50) | PARP15PARP10TNKS2PARP2SMN1; SMN2 | |
| SCHEMBL11652110 | 0.70 | PARP15 (0.45) | PARP15PARP10TNKS2PARP2SMN1; SMN2 | |
| SCHEMBL11650085 | 0.68 | PARP15 (0.49) | PARP15PARP10TNKS2PARP2SMN1; SMN2 | |
| SCHEMBL20518826 | 0.67 | PARP15 (0.54) | PARP15PARP10TNKS2PARP2SMN1; SMN2 | |
| SCHEMBL14048802 | 0.64 | LMNA (0.55) | PARP15PARP10TNKS2PARP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075218-A | INSECTICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-3974286-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1976-08-10 | — | — | US | disclosed |