Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13054386 | 0.88 | LMNA (0.55) | LMNARXFP1TP53MAPTPARP15 | |
| SCHEMBL10000316 | 0.86 | LMNA (0.59) | LMNARXFP1TP53MAPTTSHR | |
| SCHEMBL13054387 | 0.83 | LMNA (0.53) | LMNARXFP1TP53MAPTPARP15 | |
| SCHEMBL13290939 | 0.81 | MAPT (0.78) | LMNARXFP1TP53MAPTTSHR | |
| SCHEMBL24619304 | 0.80 | LMNA (0.57) | LMNARXFP1TP53MAPTTSHR | |
| SCHEMBL24105990 | 0.78 | LMNA (0.68) | LMNARXFP1TP53MAPTTHRB | |
| SCHEMBL3045446 | 0.78 | LMNA (0.51) | LMNARXFP1TP53MAPTTSHR | |
| SCHEMBL796947 | 0.76 | APP (0.76) | LMNARXFP1TP53MAPTTSHR | |
| SCHEMBL31338672 | 0.76 | LMNA (0.48) | LMNARXFP1TP53MAPTTSHR | |
| SCHEMBL8739574 | 0.74 | LMNA (0.46) | LMNARXFP1TP53MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118122-A2 | COMPOUNDS AND AMYLOID PROBES THEREOF FOR THERAPEUTIC AND IMAGING USES | MOLECULAR NEUROIMAGING, LLC (US) | 2008-10-02 | — | — | WO | disclosed |