Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647749 | 1.00 | PAX8 (0.65) | PAX8ADORA1XDH | |
| SCHEMBL11651719 | 1.00 | PAX8 (0.65) | PAX8ADORA1XDH | |
| SCHEMBL11651183 | 1.00 | PAX8 (0.65) | PAX8ADORA1XDH | |
| SCHEMBL11646948 | 0.91 | PAX8 (0.79) | PAX8ADORA1 | |
| SCHEMBL13593374 | 0.84 | PAX8 (0.51) | PAX8XDH | |
| SCHEMBL31529254 | 0.78 | PAX8 (0.69) | PAX8 | |
| SCHEMBL31529157 | 0.78 | PAX8 (0.69) | PAX8 | |
| SCHEMBL31529328 | 0.77 | PAX8 (0.68) | PAX8 | |
| SCHEMBL31529313 | 0.77 | PAX8 (0.68) | PAX8 | |
| Krn5500 SCHEMBL29395534 | 0.76 | PAX8 (0.42) | PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086416-A | ANTITUMOR | STANFORD RESEARCH INSTITUTE (US) | 1978-04-25 | — | — | US | claimed |
| US-4086416-A | ANTITUMOR | STANFORD RESEARCH INSTITUTE (US) | 1978-04-25 | — | — | US | disclosed |