Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529254 | 0.99 | PAX8 (0.69) | PAX8HDAC1HDAC2AURKABRD4 | |
| SCHEMBL31529157 | 0.99 | PAX8 (0.69) | PAX8HDAC1HDAC2AURKABRD4 | |
| SCHEMBL31529328 | 0.98 | PAX8 (0.68) | PAX8HDAC1HDAC2AURKABRD4 | |
| SCHEMBL31529249 | 0.92 | PAX8 (0.59) | PAX8HDAC1HDAC2AURKABRD4 | |
| SCHEMBL31529336 | 0.88 | PAX8 (0.60) | PAX8HDAC1HDAC2BRD4SMN1; SMN2 | |
| SCHEMBL31529331 | 0.87 | PAX8 (0.54) | PAX8HDAC1HDAC2AURKABRD4 | |
| SCHEMBL31529119 | 0.87 | PAX8 (0.54) | PAX8HDAC1HDAC2AURKABRD4 | |
| SCHEMBL31529348 | 0.87 | PAX8 (0.58) | PAX8HDAC1HDAC2BRD4SMN1; SMN2 | |
| SCHEMBL31529219 | 0.86 | PAX8 (0.58) | PAX8HDAC1HDAC2BRD4SMN1; SMN2 | |
| SCHEMBL31529304 | 0.85 | PAX8 (0.57) | PAX8HDAC1HDAC2BRD4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |