⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438921 | 1.00 | — | — | |
| SCHEMBL3972621 | 0.88 | SIRT2 (0.49) | — | |
| SCHEMBL12951363 | 0.80 | — | — | |
| SCHEMBL5670125 | 0.80 | — | — | |
| SCHEMBL3661073 | 0.77 | SIRT2 (0.39) | — | |
| SCHEMBL27321507 | 0.76 | PTGS2 (0.31) | — | |
| SCHEMBL27321490 | 0.76 | PRKCA (0.33) | — | |
| SCHEMBL15477335 | 0.75 | PIK3CD (0.34) | — | |
| SCHEMBL12935402 | 0.75 | PRKCA (0.35) | — | |
| SCHEMBL21464117 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059205-A1 | Heterocyclic Compounds and Methods of Use | AMGEN INC. (US) | 2025-02-20 | — | — | US | disclosed |
| EP-4329757-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| CN-117561063-A | Heterocyclic compounds and methods of use | 安进公司 | 2024-02-13 | — | — | CN | disclosed |
| US-20150266814-A1 | METHODS, COMPOUNDS, AND COMPOSITIONS FOR DELIVERING 1,3-PROPANEDISULFONIC ACID | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2015-09-24 | — | — | US | disclosed |
| US-9051248-B2 | Methods, compounds, and compositions for delivering 1,3-propanedisulfonic acid | BHI LIMITED PARTNERSHIP (CA) | 2015-06-09 | — | — | US | disclosed |
| CN-102471248-B | Methods, compounds, and compositions for delivering 1,3-propan ed isulfonic acid | BELLUS HEALTH INTERNATIONAL LTD | 2015-01-07 | — | — | CN | disclosed |
| US-20120208850-A1 | METHODS, COMPOUNDS, AND COMPOSITIONS FOR DELIVERING 1,3-PROPANEDISULFONIC ACID | BELLUS HEALTH INC. (CA) | 2012-08-16 | — | — | US | disclosed |
| EP-2464626-A1 | METHODS, COMPOUNDS, AND COMPOSITIONS FOR DELIVERING 1,3-PROPAN ED ISULFONIC ACID | Bellus Health Inc. (CA) | 2012-06-20 | — | — | EP | disclosed |
| CN-102471248-A | Methods, compounds, and compositions for delivering 1,3-propan ed isulfonic acid | BELLUS HEALTH INTERNATIONAL LTD | 2012-05-23 | — | — | CN | disclosed |
| WO-2011017800-A1 | METHODS, COMPOUNDS, AND COMPOSITIONS FOR DELIVERING 1,3-PROPAN ED ISULFONIC ACID | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2011-02-17 | — | — | WO | disclosed |
| WO-2009052191-A1 | INTERNALLY MASKED NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE | XENOPORT, INC. (US) | 2009-04-23 | — | — | WO | disclosed |
| US-20090099253-A1 | Internally Masked Neopentyl Sulfonyl Ester Cyclization Release Prodrugs of Acamprosate, Compositions Thereof, and Methods of Use | XENOPORT, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| US-4208331-A | Synthesis of optically active vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1980-06-17 | — | — | US | disclosed |
| US-4208332-A | Synthesis of optically active vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1980-06-17 | — | — | US | disclosed |
| US-4189612-A | S-(+) 2,3,6-trimethyl-5-(2,2,4-trimethyl-1,3-dioxolane-4-ethyl)phenol | HOFFMANN-LA ROCHE INC. (US) | 1980-02-19 | — | — | US | disclosed |
| US-4182719-A | Synthesis of optically active vitamin E | HOFFMAN-LA ROCHE INC. (US) | 1980-01-08 | — | — | US | disclosed |
| US-4151177-A | Synthesis of optically active vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1979-04-24 | — | — | US | disclosed |
| US-4113740-A | Synthesis of optically active vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1978-09-12 | — | — | US | disclosed |