SCHEMBL11650283

SCHEMBL11650283

CCCCN1C(=O)CC(=O)N(c2ccc(NC(C)=O)cc2)C1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN2A Q99250 1/20 0.45
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 4/20 0.42
MAPT P10636 3/20 0.42
MEN1 O00255 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
GFER P55789 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
NPC1 O15118 1/20 0.41
HPGD P15428 3/20 0.40
POLB P06746 3/20 0.40
RECQL P46063 1/20 0.40
CCKBR P32239 1/20 0.40
CHRNA10 Q9GZZ6 1/20 0.40
CHRNA9 Q9UGM1 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HSP90AA1 P07900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10499435 0.82 POLB (0.48) SCN2AKMT2AALDH1A1MAPTMEN1
SCHEMBL12013774 0.81 CA12 (0.48) SCN2AKMT2AALDH1A1MAPTMEN1
SCHEMBL5447443 0.80 MAPT (0.45) KMT2AALDH1A1MAPTMEN1KDM4E
SCHEMBL11160362 0.79 MEN1 (0.44) KMT2AMAPTMEN1KDM4EGAA
SCHEMBL5451996 0.79 NPC1 (0.55) KMT2AALDH1A1MAPTMEN1KDM4E
SCHEMBL11596316 0.77 CYP1A1 (0.36) KMT2AMAPTMEN1KDM4EGAA
SCHEMBL11596313 0.75 NR1I2 (0.39) KMT2AMAPTMEN1KDM4EGAA
SCHEMBL10498464 0.74 POLB (0.50) SCN2AKMT2AALDH1A1MAPTMEN1
SCHEMBL5145641 0.74 MAPT (0.55) KMT2AALDH1A1MAPTMEN1KDM4E
SCHEMBL3420629 0.70 MAPT (0.49) KMT2AALDH1A1MAPTMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4097475-A FOR POLYESTERS AND BLENDS WITH CELLULOSE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-06-27 US disclosed