Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145641 | 0.94 | MAPT (0.55) | NPC1RAB9ASMN1; SMN2MAPTUSP2 | |
| SCHEMBL17717965 | 0.89 | MAPT (0.62) | NPC1RAB9ASMN1; SMN2MAPTUSP2 | |
| SCHEMBL17717923 | 0.87 | MEN1 (0.56) | MAPTUSP2MEN1KMT2AKDM4E | |
| SCHEMBL8348821 | 0.87 | MAPT (0.45) | NPC1RAB9ASMN1; SMN2MAPTUSP2 | |
| SCHEMBL5447443 | 0.87 | MAPT (0.45) | NPC1RAB9ASMN1; SMN2MAPTUSP2 | |
| SCHEMBL10797889 | 0.85 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2MAPTUSP2 | |
| SCHEMBL8635136 | 0.85 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2MAPTUSP2 | |
| SCHEMBL11160362 | 0.85 | MEN1 (0.44) | NPC1RAB9ASMN1; SMN2MAPTUSP2 | |
| SCHEMBL12013774 | 0.85 | CA12 (0.48) | NPC1RAB9ASMN1; SMN2MAPTUSP2 | |
| SCHEMBL11880990 | 0.85 | MAPT (0.45) | NPC1RAB9ASMN1; SMN2MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | claimed |
| US-4097475-A | FOR POLYESTERS AND BLENDS WITH CELLULOSE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-4062836-A | YELLOW | CIBA-GEIGY CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | KRT18, NDUFB5, NDUFB7 | NPC1 4755/4885RAB9A 4652/4885SMN1; SMN2 3654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.