SCHEMBL5145641

SCHEMBL5145641

CCCCCCCCCCCCN1C(=O)CC(=O)N(c2ccccc2)C1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.55
USP2 O75604 3/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
KDM4E B2RXH2 1/20 0.55
POLB P06746 1/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HTT P42858 3/20 0.45
HSD17B10 Q99714 2/20 0.45
GAA P10253 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALDH1A1 P00352 3/20 0.44
LMNA P02545 2/20 0.44
HPGD P15428 2/20 0.44
TSHR P16473 1/20 0.44
CNR2 P34972 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5451996 0.94 NPC1 (0.55) MAPTUSP2MEN1KMT2AKDM4E
SCHEMBL17717965 0.93 MAPT (0.62) MAPTUSP2MEN1KMT2AKDM4E
SCHEMBL8348821 0.90 MAPT (0.45) MAPTUSP2MEN1KMT2AKDM4E
SCHEMBL17717923 0.85 MEN1 (0.56) MAPTUSP2MEN1KMT2AKDM4E
SCHEMBL11880990 0.82 MAPT (0.45) MAPTUSP2MEN1KMT2AKDM4E
SCHEMBL11654107 0.82 MAPT (0.47) MAPTUSP2MEN1KMT2AKDM4E
SCHEMBL5443739 0.82 HPGD (0.46) MAPTUSP2MEN1KMT2AHTT
SCHEMBL5447443 0.81 MAPT (0.45) MAPTUSP2MEN1KMT2AKDM4E
SCHEMBL10797889 0.80 NPC1 (0.68) MAPTUSP2MEN1KMT2AKDM4E
SCHEMBL8635136 0.80 NPC1 (0.52) MAPTUSP2MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7270928-B2 Isocyanate composition, microcapsule and production method thereof, and recording material FUJIFILM CORPORATION (JP) 2007-09-18 US disclosed
US-20050153839-A1 Isocyanate composition, microcapsule and production method thereof, and recording material FUJI PHOTO FILM CO., LTD. 2005-07-14 US disclosed
US-20040091810-A1 Microcapsule, and heat-sensitive recording material and multicolor heat-sensitive recording material using the same FUJI PHOTO FILM CO., LTD. 2004-05-13 US disclosed
US-6303259-B1 FOR COLOR DUPLICATORS, COLOR PRINTERS, ETC MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2001-10-16 US disclosed
US-5916680-A CONTAINING A DIAZO COMPOUND OR AN ELECTRON DONATIVE DYE PRECURSOR, WHEREIN THE CAPSULE WALL IS COMPOSED OF AT LEAST ONE POLYMER OBTAINED BY POLYMERIZATION OF AN ISOCYANATE COMPOUND CONTAINING AN ADDUCT FUJI PHOTO FILM CO., LTD (JP) 1999-06-29 US disclosed
US-5547806-A ADDING A DIALKYL SULFATE AND A POLYFUNCTIONAL ISOCYANATE COMPOUND; EMULSIFICATION; POLYMERIZATION; MICROENCAPSULATION FUJI PHOTO FILM CO., LTD. (JP) 1996-08-20 US disclosed
US-5492789-A USING ALKYL GLUOCISDE EMULSIFIER; STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1996-02-20 US disclosed