Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573950 | 0.85 | CHRNB2 (0.51) | CHRNB2CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11692503 | 0.80 | SIGMAR1 (0.45) | CHRNB2CHRNA4SIGMAR1 | |
| SCHEMBL11700742 | 0.76 | CHRNB2 (0.40) | CHRNB2CHRNA4SIGMAR1 | |
| SCHEMBL11650898 | 0.76 | SIGMAR1 (0.53) | SIGMAR1MEN1CYP1A2CYP3A4KMT2A | |
| SCHEMBL11699947 | 0.76 | CHRNB2 (0.56) | CHRNB2CHRNA4 | |
| SCHEMBL11541762 | 0.76 | KDM4E (0.51) | SIGMAR1KDM4EATM | |
| SCHEMBL6545918 | 0.76 | CHRNB2 (0.56) | CHRNB2CHRNA4 | |
| SCHEMBL11705873 | 0.76 | CHRNB2 (0.59) | CHRNB2CHRNA4SIGMAR1 | |
| SCHEMBL11651367 | 0.76 | SIGMAR1 (0.51) | SIGMAR1MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11703659 | 0.75 | CHRNB2 (0.54) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082744-A | CNS, ANALGESICS, ANTITUSSIVE, SEDATIVES | NIHON IYAKUHIN KOGYO CO., LTD. (JA) | 1978-04-04 | — | — | US | disclosed |
| US-4008219-A | CNS ANALGESIC, ANTITUSSIVE, SEDATIVE | NIHON IYAKUHIN KOGYO CO., LTD. (JA) | 1977-02-15 | — | — | US | disclosed |