Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 12/20 | 1.00 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652970 | 0.85 | GAA (0.73) | GAAMAPK10MAPTALDH1A1L3MBTL1 | |
| SCHEMBL9163270 | 0.78 | GAA (0.62) | GAAPOLBMAPTALDH1A1LMNA | |
| SCHEMBL10736333 | 0.77 | GAA (0.62) | GAAMAPK10POLBMAPTALDH1A1 | |
| SCHEMBL30019705 | 0.76 | GAA (0.61) | GAAMAPK10POLBMAPTALDH1A1 | |
| SCHEMBL11083170 | 0.74 | GAA (0.58) | GAAPOLBMAPTALDH1A1LMNA | |
| SCHEMBL8354029 | 0.74 | GAA (0.58) | GAAMAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL8769893 | 0.73 | GAA (0.58) | GAAPOLBMAPTALDH1A1LMNA | |
| SCHEMBL15976549 | 0.72 | GAA (0.77) | GAAMAPK10L3MBTL1KMT2AMEN1 | |
| SCHEMBL31546026 | 0.71 | GAA (0.55) | GAAMAPK10MAPTALDH1A1NPC1 | |
| SCHEMBL13527924 | 0.70 | TDP1 (0.80) | GAAMAPK10MAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4094741-A | CULTURES, ASYMMETRIC HYDROLYSIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1978-06-13 | — | — | US | disclosed |