Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 11/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163270 | 0.85 | GAA (0.62) | GAATDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL10737695 | 0.81 | GAA (0.48) | GAATDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL11083170 | 0.81 | GAA (0.58) | GAATDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL8769893 | 0.80 | GAA (0.58) | GAATDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL11652970 | 0.80 | GAA (0.73) | GAAL3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL7766454 | 0.77 | GAA (0.48) | GAATDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL11651041 | 0.77 | GAA (1.00) | GAAL3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL13527924 | 0.76 | TDP1 (0.80) | GAATDP1ALDH1A1MAPTKMT2A | |
| SCHEMBL1014744 | 0.75 | TDP1 (0.67) | GAATDP1ALDH1A1MAPTKMT2A | |
| SCHEMBL9690927 | 0.75 | TDP1 (0.67) | GAATDP1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4672101-A | Polyepoxy aromatic hydantoins | THE DOW CHEMICAL COMPANY (US) | 1987-06-09 | — | — | US | disclosed |
| US-4094741-A | CULTURES, ASYMMETRIC HYDROLYSIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1978-06-13 | — | — | US | disclosed |