Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163270 | 0.81 | GAA (0.62) | GAATDP1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10736333 | 0.80 | GAA (0.62) | GAATDP1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11083170 | 0.77 | GAA (0.58) | GAATDP1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11652970 | 0.77 | GAA (0.73) | GAAALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL11651041 | 0.73 | GAA (1.00) | GAAALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL13527924 | 0.73 | TDP1 (0.80) | GAATDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL1014744 | 0.72 | TDP1 (0.67) | GAATDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL8076297 | 0.70 | KIF11 (0.56) | GAATDP1ALDH1A1MAPTPOLB | |
| SCHEMBL11276118 | 0.69 | ALDH1A1 (0.43) | GAATDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL9690927 | 0.69 | TDP1 (0.67) | GAATDP1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647630-B1 | Process for producing 5-arylhydantoins | SHOWA DENKO KK (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5606071-A | Process for preparing 5-arylhydantoins using 5-hydantoin, a halogenating agent and p-phenol | SHOWA DENKO K.K. (JP) | 1997-02-25 | — | — | US | disclosed |
| EP-0647630-A1 | Process for producing 5-arylhydantoins | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1995-04-12 | — | — | EP | disclosed |