SCHEMBL11651069

SCHEMBL11651069

O=c1cc(-c2ccccc2)oc2cccc(OCCO)c12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
AR P10275 4/20 0.67
CYP3A4 P08684 4/20 0.67
KDM4E B2RXH2 4/20 0.67
MAPT P10636 3/20 0.67
HPGD P15428 3/20 0.67
TP53 P04637 2/20 0.67
HSD17B10 Q99714 2/20 0.67
BCHE P06276 1/20 0.66
ACHE P22303 1/20 0.66
SIGMAR1 Q99720 5/20 0.64
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
CYP1A2 P05177 2/20 0.59
CYP1A1 P04798 1/20 0.59
PKM P14618 1/20 0.59
ALOX15 P16050 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
CYP1B1 Q16678 1/20 0.59
FTO Q9C0B1 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11656201 0.88 AR (0.65) ALDH1A1ARCYP3A4KDM4EMAPT
SCHEMBL9390377 0.88 AR (0.65) ALDH1A1ARCYP3A4KDM4EMAPT
SCHEMBL9207377 0.87 AR (0.64) ALDH1A1ARCYP3A4KDM4EMAPT
SCHEMBL8787218 0.87 SIGMAR1 (0.66) ALDH1A1ARCYP3A4KDM4EMAPT
SCHEMBL9140082 0.87 ALDH1A1 (0.67) ALDH1A1ARCYP3A4KDM4EMAPT
SCHEMBL11659326 0.86 ALDH1A1 (0.60) ALDH1A1ARCYP3A4KDM4EMAPT
SCHEMBL9141348 0.85 ALDH1A1 (0.65) ALDH1A1ARCYP3A4KDM4EMAPT
SCHEMBL9137293 0.85 ALDH1A1 (0.72) ALDH1A1ARCYP3A4KDM4EMAPT
SCHEMBL8786816 0.85 SIGMAR1 (0.63) ALDH1A1ARCYP3A4KDM4EMAPT
SCHEMBL11652574 0.85 ALDH1A1 (0.64) ALDH1A1ARCYP3A4KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4105781-A ANTIALLERGENS FOR TREATMENT OF ASTHMA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1978-08-08 US disclosed
US-4049664-A ANTIALLERGENS, ANTIASTHMATICS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-09-20 US disclosed
US-3965122-A ANTIALLERGENS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-06-22 US disclosed