Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823062 | 0.92 | MAPT (0.64) | MAPTKDM4EALDH1A1NTRK1KMT2A | |
| SCHEMBL4268936 | 0.84 | KDM4E (0.77) | MAPTKDM4EALDH1A1NTRK1KMT2A | |
| SCHEMBL11648787 | 0.84 | NTRK1 (0.89) | MAPTKDM4EALDH1A1NTRK1KMT2A | |
| SCHEMBL14148384 | 0.82 | KDM4E (0.73) | MAPTKDM4EALDH1A1NTRK1KMT2A | |
| SCHEMBL11646356 | 0.81 | NTRK1 (0.60) | MAPTKDM4EALDH1A1NTRK1KMT2A | |
| SCHEMBL4738310 | 0.81 | ALDH1A1 (0.71) | MAPTKDM4EALDH1A1NTRK1KMT2A | |
| SCHEMBL14148528 | 0.78 | KDM4E (0.68) | MAPTKDM4EALDH1A1NTRK1KMT2A | |
| SCHEMBL6436174 | 0.78 | MAPT (0.58) | MAPTKDM4EALDH1A1KMT2ANPSR1 | |
| SCHEMBL14148621 | 0.78 | ALDH1A1 (0.72) | MAPTKDM4EALDH1A1KMT2ANPSR1 | |
| SCHEMBL16595137 | 0.77 | NTRK1 (1.00) | MAPTKDM4EALDH1A1NTRK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4113731-A | PHOTOGRAPHIC EMULSION STABILIZERS | GRUPPO LEPETIT S.P.A. (IT) | 1978-09-12 | — | — | US | disclosed |