Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 17/20 | 0.63 |
| ▸ | CCR2 | P41597 | 1/20 | 0.57 |
| ▸ | WDR5 | P61964 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11650550 | 0.84 | ACLY (0.67) | ACLYCCR2WDR5F2PRSS1 | |
| SCHEMBL11655008 | 0.78 | HSD17B10 (0.42) | ACLYCCR2WDR5 | |
| SCHEMBL14433929 | 0.78 | ACLY (0.72) | ACLYCCR2WDR5 | |
| SCHEMBL21999815 | 0.78 | ACLY (1.00) | ACLYWDR5F2PRSS1PRSS2 | |
| SCHEMBL22005133 | 0.75 | ACLY (0.62) | ACLYCCR2 | |
| SCHEMBL21930836 | 0.75 | ACLY (1.00) | ACLY | |
| SCHEMBL17351953 | 0.75 | ACLY (0.67) | ACLYF2PRSS1PRSS2PRSS3 | |
| SCHEMBL21999962 | 0.74 | ACLY (1.00) | ACLY | |
| SCHEMBL11656512 | 0.74 | ACLY (0.42) | ACLYCCR2WDR5 | |
| SCHEMBL9930726 | 0.73 | CCR2 (1.00) | ACLYCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123553-A | ANTHELMINTICS | HOFFMANN-LA ROCHE INC. (US) | 1978-10-31 | — | — | US | claimed |
| US-4034110-A | Anthelmintics effective against liver flukes | HOFFMANN-LA ROCHE INC. (US) | 1977-07-05 | — | — | US | claimed |
| US-4123553-A | ANTHELMINTICS | HOFFMANN-LA ROCHE INC. (US) | 1978-10-31 | — | — | US | disclosed |
| US-4034110-A | Anthelmintics effective against liver flukes | HOFFMANN-LA ROCHE INC. (US) | 1977-07-05 | — | — | US | disclosed |