Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | CTSS | P25774 | 5/20 | 0.52 |
| ▸ | CTSK | P43235 | 4/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057456 | 1.00 | PTPN1 (0.54) | PTPN1CTSSCTSKITGB3ITGA2B | |
| SCHEMBL9646827 | 1.00 | PTPN1 (0.54) | PTPN1CTSSCTSKITGB3ITGA2B | |
| SCHEMBL29397682 | 1.00 | PTPN1 (0.54) | PTPN1CTSSCTSKITGB3ITGA2B | |
| SCHEMBL29400153 | 1.00 | PTPN1 (0.54) | PTPN1CTSSCTSKITGB3ITGA2B | |
| SCHEMBL29787421 | 0.91 | PLG (0.50) | PTPN1CTSSCTSKITGB3ITGA2B | |
| SCHEMBL4217387 | 0.89 | CTSS (0.51) | PTPN1CTSSCTSKITGB3ITGA2B | |
| SCHEMBL4217382 | 0.89 | CTSS (0.51) | PTPN1CTSSCTSKITGB3ITGA2B | |
| SCHEMBL29398157 | 0.89 | PTPN1 (0.54) | PTPN1CTSSCTSKITGB3ITGA2B | |
| SCHEMBL29787395 | 0.88 | PLG (0.49) | PTPN1CTSSCTSKACEPLG | |
| SCHEMBL10941364 | 0.87 | PLG (0.56) | PTPN1CTSSCTSKPLGHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829949-A | Compositions for detecting or measuring analytes | 伯蒂斯有限公司 | 2023-09-29 | — | — | CN | disclosed |
| US-9763953-B2 | Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment | NEURODYN LIFE SCIENCES INC. (CA) | 2017-09-19 | — | — | US | disclosed |
| US-20130210808-A1 | CHOLINERGIC ENHANCERS WITH IMPROVED BLOOD-BRAIN BARRIER PERMEABILITY FOR THE TREATMENT OF DISEASES ACCOMPANIED BY COGNITIVE IMPAIRMENT | GALANTOS PHARMA GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20090253654-A1 | CHOLINERGIC ENHANCERS WITH IMPROVED BLOOD-BRAIN BARRIER PERMEABILITY FOR THE TREATMENT OF DISEASES ACCOMPANIED BY COGNITIVE IMPAIRMENT | GALANTOS PHARMA GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090253654-A1 | CHOLINERGIC ENHANCERS WITH IMPROVED BLOOD-BRAIN BARRIER PERMEABILITY FOR THE TREATMENT OF DISEASES ACCOMPANIED BY COGNITIVE IMPAIRMENT | GALANTOS PHARMA GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-4127518-A | ANALGESIC | VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY | 1978-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253654-A1 | CHOLINERGIC ENHANCERS WITH IMPROVED BLOOD-BRAIN BARRIER PERMEABILITY FOR THE TREATMENT OF DISEASES ACCOMPANIED BY COGNITIVE IMPAIRMENT | ACHE, BCHE, COMT | PTPN1 4867/4885CTSS 289/4885CTSK 808/4885 |
| US-20130210808-A1 | CHOLINERGIC ENHANCERS WITH IMPROVED BLOOD-BRAIN BARRIER PERMEABILITY FOR THE TREATMENT OF DISEASES ACCOMPANIED BY COGNITIVE IMPAIRMENT | ACHE, BCHE, COMT | PTPN1 4867/4885CTSS 289/4885CTSK 808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.