Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1079840 | 0.86 | EGLN1 (0.56) | SMN1; SMN2ALDH1A1KDM4EEGLN1HPGD | |
| SCHEMBL3758192 | 0.80 | HPGD (0.47) | SMN1; SMN2ALDH1A1HTTKDM4EEGLN1 | |
| SCHEMBL1080724 | 0.76 | QPCT (0.44) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL1081560 | 0.75 | CA12 (0.47) | ALDH1A1KDM4EEGLN1PKML3MBTL1 | |
| SCHEMBL1165214 | 0.73 | EGLN3 (0.59) | SMN1; SMN2ALDH1A1KDM4EEGLN1HPGD | |
| SCHEMBL3762383 | 0.72 | EGLN3 (0.57) | SMN1; SMN2ALDH1A1EGLN1HPGDGLA | |
| SCHEMBL1082293 | 0.71 | EGLN1 (0.59) | EGLN1 | |
| SCHEMBL29802080 | 0.69 | KMT2A (0.78) | SMN1; SMN2ALDH1A1HTTKDM4EGAA | |
| SCHEMBL15595269 | 0.69 | KMT2A (0.78) | SMN1; SMN2ALDH1A1HTTKDM4EGAA | |
| SCHEMBL1081723 | 0.68 | EGLN1 (0.61) | ALDH1A1KDM4EEGLN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110039895-A1 | PROLYL HYDROXYLASE INHIBITORS | Glaxo Smith Kline LLC., a corporation | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039895-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, EGLN3, EGLN2 | SMN1; SMN2 3216/4885ALDH1A1 103/4885HTT 2118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.