Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | STAMBP | O95630 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760876 | 0.82 | EGLN3 (0.54) | EGLN3HPGDHSD17B10EGLN1VEGFA | |
| SCHEMBL3758192 | 0.81 | HPGD (0.47) | HPGDHSD17B10SMN1; SMN2EGLN1ALDH1A1 | |
| SCHEMBL3755178 | 0.79 | PDGFRB (0.52) | EGLN3PDGFRBPDGFRAMAPT | |
| SCHEMBL3396850 | 0.73 | EGLN3 (1.00) | EGLN3EGLN1VEGFAFLT1 | |
| SCHEMBL1165214 | 0.73 | EGLN3 (0.59) | EGLN3HPGDHSD17B10SMN1; SMN2EGLN1 | |
| SCHEMBL1165232 | 0.72 | SMN1; SMN2 (0.43) | HPGDHSD17B10SMN1; SMN2EGLN1ALDH1A1 | |
| SCHEMBL70720 | 0.72 | EGLN1 (0.62) | HPGDEGLN1ALDH1A1LMNAMAPT | |
| SCHEMBL3752845 | 0.72 | EGLN3 (0.42) | EGLN3HPGDHSD17B10SMN1; SMN2EGLN1 | |
| SCHEMBL3518478 | 0.71 | EGLN3 (0.50) | EGLN3HPGDHSD17B10SMN1; SMN2EGLN1 | |
| SCHEMBL3518821 | 0.71 | EGLN3 (0.49) | EGLN3HPGDHSD17B10SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305154-A1 | Prolyl Hydroxylase Inhibitors | GLAXOSMITHKLINE LLC | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305154-A1 | Prolyl Hydroxylase Inhibitors | HIF1AN, EGLN3, EGLN2 | EGLN3 2/4885HPGD 58/4885HSD17B10 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.